SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA
- русский язык имя
- английское имяSUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA
- CAS №137348-11-9
- CBNumberCB0972460
- ФормулаC65H102N18O15S
- мольный вес1407.7
- EINECS251-545-8
- файл Mol137348-11-9.mol
химическое свойство
| температура хранения | −20°C |
| растворимость | 0.1 M acetic acid: soluble1mg/mL |
| форма | powder |
| цвет | white |
| БРН | 5153552 |
| UNSPSC Code | 12352200 |
| NACRES | NA.32 |
SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA химические свойства, назначение, производство
Использование
Substance P acetate salt hydrate has been:- used as a neurokinin 1 (NK1) receptor agonist for the activation of spinal nociceptive circuitry in mice
- administered in central nucleus (ACE) in rat to study its positive reinforcing effects
- used as an inhibitor of myosin light chain kinase in isolated lymphatic vessels from rat
Общее описание
Substance P is a small peptide produced by macrophages, lymphocytes, eosinophils, dendritic cells and nerves. It is part of the neurokinin group.Биохимия/физиол Действия
NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.