What is the use and synthesis of Diethyl acetamidomalonate?

Diethyl acetamidomalonate (DEAM) is a white powdery substance characterized by low water solubility, but possessing good solvency in lower alcohols and chloroform. It serves as a starting material for racemates including both, natural and unnatural α-amino acids or hydroxycarboxylic acids. Shaw and Nolan reported a 98% yield by conversion of diethyl oximinomalonate-sodium acetate complex.

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