Exploring Trimethylamine Hydrochloride: A Key Compound in Chemical Research

Introduction

Trimethylamine Hydrochloride, an organic compound, is a hygroscopic tertiary amine with a fishy odour. It is a white crystalline powder highly soluble in water and alcohol. It is commonly used as a reagent in organic chemistry due to its role as a methylating agent. In addition, it has many uses, including in the synthesis of choline, in plant growth herbicides or regulators, and in dye leveling agents.

The research of Trimethylamine Hydrochloride

The nicotine-like compound tetramethylammonium iodide (TMA) and trimethylamine hydrochloride (TRIMA) depress the responses of the nictitating membrane to stimulation of the Postganglionic cervical sympathetic nerve. This effect is due to the s~npathotytic activity of the compounds, which is approximately ten times greater for TMA than for TRIMA.

TRIMA in a dose of 0.5 mmole/kg did not give statistically significant changes in the response of the nictitating membrane. In a dose of 2.5 mmol/kg, the compound significantly reduced the contractions of the nictitating membrane produced by stimulation of the s:~anpathetic nerve but had no significant effect on contractions caused by adrenalin. The research results suggest that inhibition of contractions of the nictitating membrane caused by stimulation of the postgxnglionic sympathetic nerve is due to the sympathol3/cic activity of TMA and TRIMA. The basis for this assertion is that this particular effect was not accompanied in any series of experiments by a statistically significant decrease in the response of the membrane to L-adrenalin.

Four chemical compounds were previously shown to be attractants to Hippelales eye gnats, and houseflies were evaluated against Fannia femoralis (Stein). Two of the compounds, trimethylamine hydrochloride and n-butyric acid were determined to be the principal attractants against this fly. A composition containing trimethylamine hydrochloride (yielding trimethylamine in the presence of water), n-butyric acid, and an anchovy meal inert carrier proved highly attractive. To evaluate the practical use of the synthetic fly attractant (SFA) formulation, a large-scale trial over an entire poultry ranch was implemented using SFA formulation and a sugar toxicant (as a killing agent) in specially designed traps. Within 2 weeks after initiating S FA-toxicant treatments, a significant reduction in the F.femoralis population from the pretreatment level occurred. This high level of reduction prevailed during the remainder of the treatment period.

Reference

[1] Miyake M, Motonami H, Shiomi S, et al. Electrodeposition of purified aluminum coatings from dimethylsulfone–AlCl3 electrolytes with trimethylamine hydrochloride[J]. Surface and Coatings Technology, 2012, 206(19-20): 4225-4229.

[2] M S Mulla, Y S Hwang, H Axelrod. “Field evaluation of chemical attractants against the flyFannia femoralis (Diptera: Muscidae).” Journal of Chemical Ecology 10 2 (1984): 349–60.

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