1-Dibenzofuranylboronic acid: properties, applications and safety

General Description

1-Dibenzofuranylboronic acid is a valuable reagent with unique properties that make it suitable for various applications. It has the ability to form stable boronate esters, exhibit good thermal stability, and act as a Lewis acid catalyst, making it ideal for use in Suzuki-Miyaura cross-coupling reactions and other organic synthesis processes. It is also used in the production of important compounds for electronic devices and pharmaceuticals. When handled and used properly, 1-Dibenzofuranylboronic acid is considered safe, but appropriate safety precautions should always be taken to minimize potential hazards.

Figure 1. 1-Dibenzofuranylboronic acid

Properties

1-Dibenzofuranylboronic acid is a chemical compound with several notable properties. It belongs to the boronic acid family and is derived from dibenzofuran, a heterocyclic aromatic compound. This compound is commonly used in organic synthesis and pharmaceutical research due to its unique characteristics. One of the key properties of 1-Dibenzofuranylboronic acid is its ability to form stable boronate esters through reaction with various electrophiles. This property makes it a valuable reagent for Suzuki-Miyaura cross-coupling reactions, which are widely used in the construction of carbon-carbon bonds. The resulting boronate esters are highly versatile and can undergo further transformations to generate complex molecular structures. Additionally, 1-Dibenzofuranylboronic acid exhibits good thermal stability, allowing it to withstand high temperatures during reactions without decomposition. This feature is crucial for achieving efficient and reliable synthetic processes. Furthermore, this compound possesses moderate acidity, making it suitable for catalytic applications. It can act as a Lewis acid catalyst, promoting various organic reactions such as C-C bond formation and oxidation reactions. In summary, 1-Dibenzofuranylboronic acid is a valuable compound known for its stability, reactivity, and catalytic properties. ¹

Applications

1-Dibenzofuranylboronic acid is a versatile reagent that finds its applications in various fields, including electronic devices materials preparation and organic synthesis. In the field of electronic devices, 1-Dibenzofuranylboronic Acid is used as an intermediate to synthesize dibenzo [g, p] chrysene compound, which is an important material used in Organic Light Emitting Diodes (OLEDs). These OLEDs are widely used in display technologies, such as TVs, smartphones, and computer monitors, due to their low power consumption, high brightness, and long lifespan. In organic synthesis, 1-Dibenzofuranylboronic acid is used as an intermediate to produce various chemical compounds that find applications in laboratory research and development and chemical production processes. For example, Dibenzo[b,d]furan-1-ylboronic acid is synthesized using 1-Dibenzofuranylboronic acid, which finds its application in the synthesis of natural products and pharmaceuticals. In conclusion, 1-Dibenzofuranylboronic acid is a useful reagent with a wide range of applications in electronic devices and organic synthesis. Its ability to act as an intermediate in the synthesis of important compounds makes it an essential reagent in the chemical industry and research laboratories. ^2,3

Safety

1-Dibenzofuranylboronic acid is generally considered to be a safe compound when handled and used properly. As with any chemical substance, it is important to follow appropriate safety precautions to minimize the risk of potential hazards. First and foremost, it is crucial to handle 1-Dibenzofuranylboronic acid in a well-ventilated area to prevent inhalation of any vapors or dust particles. Personal protective equipment, including safety goggles, gloves, and a lab coat, should be worn when handling this compound to prevent direct skin or eye contact. Additionally, 1-Dibenzofuranylboronic acid should be stored in a dry, cool place away from incompatible substances to avoid potential reactions or degradation. Care should be taken to prevent spills, and any spills should be cleaned up immediately using appropriate absorbent materials. Furthermore, it is essential to be familiar with the material safety data sheet (MSDS) for 1-Dibenzofuranylboronic acid and to understand its proper handling, storage, and disposal requirements. By following these safety guidelines and exercising caution, the potential risks associated with 1-Dibenzofuranylboronic acid can be effectively minimized, ensuring a safe working environment for researchers and laboratory personnel. ⁴

Reference

1. PubChem. COMPOUND SUMMARY: Dibenzo[B,D]furan-1-ylboronic acid. National Library of Medicine, PubChem CID: 17750867.

2. National Center for Biotechnology Information A blue light host material based on phenanthrene and anthracene and its application in organic electroluminescent devices. 2023, PubChem Patent Summary for CN-114805265-A.

3. National Center for Biotechnology Information. A kind of fused ring aromatic amine compound used in organic layer of OLED device and its synthesis method and application. 2023, PubChem Patent Summary for CN-113788807-A.

4. Dibenzofuran-1-boronic Acid. European Chemicals Agency, EC / List no. 829-640-6.

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