Monoclonal Anti-TNFRSF17 antibody produced in mouse

品牌Leading Biology     
货号LM13131
产品分类单克隆抗体     
产品概述    
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
形式    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
浓度    
TNFRSF17 (AAH58291, 1 a.a. ~ 184 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
纯度mouse
试剂准备    
Clear, colorless solution in phosphate buffered saline, pH 7.2.
复溶    
Identification of single nucleotide polymorphisms in the TNFRSF17 gene and their association with gastrointestinal disorders. Chae SC, et al. Mol Cells, 2010 Jan. PMID 20016944.Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. Hosgood HD 3rd, et al. Occup Environ Med, 2009 Dec. PMID 19773279.Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination. Barone F, et al. Mucosal Immunol, 2009 Nov. PMID 19741596.Local network topology in human protein interaction data predicts functional association. Li H, et al. PLoS One, 2009 Jul 29. PMID 19641626.Common variants at ten loci influence QT interval duration in the QTGEN Study. Newton-Cheh C, et al. Nat Genet, 2009 Apr. PMID 19305408.
储存条件    Human
储存溶液    Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, CD269, TNFRSF17, BCM, BCMA
应用    WB~~1:500~1000