RAT ANTI C-MYC

保存条件:-20*C
应用范围:科研试验
适应物种:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
宿主:Rabbit
抗体英文名:Anti-BAX antibody
保质期:1年
克隆性:多克隆
数量:大量
供应商:上海晶抗生物工程有限公司
规格:25 μl/100 μl/200 μl

Anti-BAX antibody
Cat. No. JK120073
Package 25 ul/100 μl/200 μul
Storage -20*C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BAX rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Fusion protein of human BAX
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
lg class Immunogen-specific rabbit IgG
Purification Antigen afinity purification

Target information
Symbol BAX
Full name BCL 2-associated X protein
Synonyms BCL2L4
Swissprot Q07812
Target Background
The protein encoded by this gene belongs to the BCL 2 protein family. BCL 2 family members form hetero- or
homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This
protein forms a heterodimer with BCL 2, and functions as an apoptotic activator. This protein is reported to interact with,
and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in
membrane potential and the release of cytochrome C. The expression of this gene is regulated by the tumor
suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Mutiple alternatively spliced transcript
variants, which encode different isoforms, have been reported for this gene.