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网站主页 化工产品目录 生物化工 抗体 ANTI-PHOSPHO-AKT1-Y315/AKT2-Y316/AKT3-Y312 POLYCLONAL ANTIBODY Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody
  • Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody

Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody

Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-11-26

北京索莱宝科技有限公司

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联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody
英文名称:
Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody
Gene ID:
207/208/10000
Subcellular Locations:
Cell membrane Cytoplasm Nucleus
Swiss Prot:
P31749/P31751/Q9Y243
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
AKT;CWS6;PKB;PKB-ALPHA;PRKBA;RAC;RAC-ALPHA
产品编号:
K006373P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
48/51/54/56kDa
交叉反应:
Human Mouse Rat
克隆类型:
Polyclonal Antibody
免疫原:
A phospho specific peptide corresponding to residues surrounding Y315 of human AKT1
宿主:
Rabbit
稀释比例:
WB 1:500-1:1000. IHC 1:50-1:100. IF 1:100-1:200.
亚型:
IgG
应用:
WB IHC IF
英文名称:
Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody

背景资料

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Anti-Phospho-AKT1-Y315/AKT2-Y316/AKT3-Y312 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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