Bakuchiol The Ingredient Alternative to Retinoids 新品

Study Protocol

In   a randomized, double-blind assessment of 44 subjects, topical bakuchiol and   retinol were compared for their ability to improve signs of photoaging. Over   12 weeks, subjects applied either 0.5% bakuchiol cream twice daily or 0.5%   retinol cream daily. High-resolution photographs were taken and analyzed at   0, 4, 8 and 12 weeks.

Subjects   also completed tolerability questionnaires to review side effects.   Additionally, in a blinded manner, a board-certified dermatologist graded   pigmentation and redness.

Test Results

Results   indicated bakuchiol was comparable to retinol in its ability to improve   photoaging; differences in effects were not statistically significant.   Bakuchiol also was better tolerated than retinol, suggesting its potential as   an alternative option.