产品编号 |
产品名称 |
产品包装 |
产品价格 |
P5435-1mg |
Recombinant Human AITR Ligand/TNFSF18 |
1mg |
26773.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Human
|
8995
|
Q9UNG2
|
E. coli
|
126aa
|
14.3kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Human AITR Ligand/TNFSF18 (Recombinant Human Activation-induced TNFR member Ligand/TNFSF18; rHuAITR Ligand/TNFSF18);重组人诱导激活TNFR成员配体/TNFSF18
|
Synonyms
|
TNFSF18; Activation-inducible TNF-related ligand; AITRLMGC138237; GITRLglucocorticoid-induced TNFR-related protein ligand; Glucocorticoid-induced TNF-related ligand; hGITRLGITR ligand; TL6AITR ligand; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18
|
Purity
|
>98% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The biological activity as determined by stimulation of IL-8 production using human PBMC is in a concentration range of 0.1-10ng/ml.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.
|
Endotoxin
|
Less than 0.1EU/μg of rHuAITR Ligand/TNFSF18 as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Cytokine
|
Background
|
TNFSF18, also named as AITRL, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family and it is encoded by the TNFSF18 gene. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. It is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 is a 14.3kDa protein, containing 126 amino acid residues and it shares 56% and 60%a.a. sequence identity with murine and rat TNFSF18, respectively.
|
Amino Acid Sequence
|
ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFIS
|
包装清单:
产品编号
|
产品名称
|
包装
|
P5435-5μg
|
Recombinant Human AITR Ligand/TNFSF18
|
5μg
|
P5435-20μg
|
Recombinant Human AITR Ligand/TNFSF18
|
20μg
|
P5435-100μg
|
Recombinant Human AITR Ligand/TNFSF18
|
100μg
|
P5435-1mg
|
Recombinant Human AITR Ligand/TNFSF18
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。