产品编号 |
产品名称 |
产品包装 |
产品价格 |
P6591-5μg |
Recombinant Human LAG-1/CCL4L1 |
5μg |
464.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Human
|
388372
|
Q8NHW4
|
E. coli
|
69aa
|
7.8kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Human LAG-1/CCL4L1 (Recombinant Human Lymphocyte Activation Gene 1 Protein/CCL4L1; rHuLAG-1/CCL4L1);重组人淋巴细胞激活蛋白1/CCL4L1
|
Synonyms
|
LAG1; CCL4L; LAG-1; SCYA4L; AT744.2; SCYA4L1; SCYA4L2; MIP-1-beta
|
Purity
|
>97% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0ng/ml, corresponding to a specific activity of >5.0×105IU/mg.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in PBS.
|
Endotoxin
|
Less than 0.1EU/μg of rHuLAG-1/CCL4L1 as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions with a NaCl concentration no less than 300mM.
|
Category
|
Chemokines
|
Background
|
C-C motif chemokine 4-like, also known as MIP-1-beta, is encoded by one of several cytokine genes clustered on the q-arm of chromosome 17 and is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The human CCL4L1 cDNA encodes a 92 amino acid (a.a.) precursor with a 23a.a. signal sequence and it shares greater than 98%a.a. sequence identity with CCL4 and CCL4L2. Recombinant Human CCL4L1 also shares 96%a.a. sequence identity with rhesus CCL4 and approximately 80~90%a.a. sequence identity with bovine, murine, rabbit, and rat CCL4.
|
Amino Acid Sequence
|
APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
|
包装清单:
产品编号
|
产品名称
|
包装
|
P6591-5μg
|
Recombinant Human LAG-1/CCL4L1
|
5μg
|
P6591-20μg
|
Recombinant Human LAG-1/CCL4L1
|
20μg
|
P6591-100μg
|
Recombinant Human LAG-1/CCL4L1
|
100μg
|
P6591-1mg
|
Recombinant Human LAG-1/CCL4L1
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。