Recombinant Murine CTACK/CCL27

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

20301

Q9Z1X0

E. coli

95aa

10.9kDa

－

About this Antibody

Name

Recombinant Murine CTACK/CCL27 (Recombinant Murine Cuteaneous T-cell Attracting Chemokine/CCL27; rMuCTACK/CCL27)；Recombinant Mouse CTACK/CCL27 ; 重组小鼠皮肤T细胞虏获趋化因子/CCL27

Synonyms

CTACK; ILC; ALP; C-C motif chemokine 27; chemokine (C-C motif) ligand 27; CTACKSmall-inducible cytokine A27; CTAK; cutaneous T-cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESKINE; ESkine; IL-11 Ralpha-locus chemokine; ILCCC chemokine ILC; PESKY; SCYA27IL-11 R-alpha-locus chemokine; skinkine; Skinkine; small inducible cytokine subfamily A (Cys-Cys), member 27

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered lyophilized (freeze-dried) liquid-like powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 2X PBS, pH7.4, with 5% trehalose.

Endotoxin

Less than 1EU/μg of rMuCTACK/CCL27 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL27, also named IL-11 R-alpha-locus chemokine (ILC), skinkine, eskine and cutaneous T-cell-attracting chemokine (CTACK), is a small cytokine belonging to the CC chemokine family. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin and it elicits its chemotactic effects by binding to the chemokine receptor CCR10. CCL27 can attract skin-associated memory T-lymphocytes. Studies showed it may play a role in mediating homing of lymphocytes to cutaneous sites and cell migration during embryogenesis. Mature mouse CCL27 is a 95 amino acid (a.a.) protein that shares 57%a.a. and 87%a.a. sequence identity with human and rat CCL27, respectively. It shares 18%~31%a.a. sequence identity with other mouse CC chemokines.

Amino Acid Sequence

LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN

产品编号

产品名称

包装

P6843-5μg

Recombinant Murine CTACK/CCL27

5μg

P6843-20μg

Recombinant Murine CTACK/CCL27

20μg

P6843-100μg

Recombinant Murine CTACK/CCL27

100μg

P6843-1mg

Recombinant Murine CTACK/CCL27

1mg

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说明书

1份