Src Rabbit Monoclonal Antibody

来源

用途

交叉反应性

分子量

Rabbit

WB, IF, IHC, ICC

H, R

60.0kDa

WB

IP

IF

IHC

ICC

FC

ELISA

ChIP

1:1,000

-

1:50-1:200

1:50-1:200

1:50-1:200

-

-

-

About this Antibody

Name

Src Rabbit Monoclonal Antibody

Category

Rabbit Monoclonal Antibody (RabMAb); Primary antibody

Isotype

IgG

Purification

Affinity purification

About the Immunogen

Immunogen

Recombinant protein

Gene ID

6714(Human); 83805(Rat)

SwissProt

P12931(Human); Q9WUD9(Rat)

Synonyms

ASV; SRC1; c-SRC; p60-Src

Category

MAPK

Background

The major translational products of the Src gene family are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences. By virtue of their common structural motifs, the Src family is composed of nine members in vertebrates, including c-Src, c-Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck and Blk. Src family kinases, which contain an amino-terminal cell membrane anchor followed by SH3 and SH2 domains, transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family members are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular locations of Src family kinases may be important for the regulation of specific cellular processes, such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.

产品编号

产品名称

包装

AF1831

Src Rabbit Monoclonal Antibody

50μl

AZ050

Western一抗稀释液

50ml

-

说明书

1份