AMPK ALPHA 1 RABBIT MONOCLONAL ANTIBODY

背景资料

AMPKα （PRKAA1） belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase （AMPK）. AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.

应用类型

The antibody can be used for ELISA （0.25 ug/ml）， Western blotting （2.5  5.0 ug/ml） and Immunohistochemistry （5 -25 ug/ml）.

免疫原

Synthetic peptide corresponding to the amino acid residues surrounding S487 of human PRKAA1

来源宿主

兔

反应性

经检测验证，可与人种属来源的AMPKα蛋白发生免疫反应.

保存建议

提供的AMPKα抗体产品为100 ug 无色溶液，其浓度为0.25 mg/ml，溶解于包含有0.09% （W/V） 叠氮钠的PBS缓冲液中.请将该AMPKα抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.