Recombinant Human CTLA-4 Protein (His Tag), HPLC-verified

Recombinant Human CTLA4 / CD152 Protein (His Tag)

￥1660 100μg 起订

￥10760 1mg 起订

北京更新日期：2026-08-20

北京义翘神州科技股份有限公司(Sino Biological Inc.)

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产品详情:

中文名称：: 重组人细胞毒性T淋巴细胞蛋白4蛋白 (His标签)

英文名称：: Recombinant Human CTLA4 / CD152 Protein (His Tag)

品牌：: 义翘神州

产地：: 北京

保存条件：: -20℃ to -80℃

纯度规格：: 90 % SDS-PAGE; 95 % SEC-HPLC; 95 % SEC-MALS

产品类别：: 肿瘤靶点蛋白

货号：: 11159-H08H

用途范围：: 科研

规格：: 100.00 µg,1.00 mg

是否进口：: 否

靶点：: CTLA4

种属：: Human

表达系统：: HEK293 Cells

Recombinant Human CTLA4 / CD152 Protein (His Tag)｜Cat:11159‑H08H

Recombinant Human CTLA4 / CD152 Protein (His Tag)

Cat No: 11159‑H08H｜Official product page: https://cn.sinobiological.com/recombinant-proteins/human-ctla-4-11159-h08h

Specifications

Purity

≥ 90 % as determined by SDS‑PAGE. ≥ 95 % as determined by SEC‑HPLC. ≥ 95 % as determined by SEC‑MALS(Routinely tested).

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Protein Construction

A DNA sequence encoding the human CTLA4 (NP005205.2) extracellular domain(Lys36‑Phe162) was fused with the a polyhistidine tag at the C‑terminus.

Accession #

NP_005205.2

Expression Host

HEK293 Cells

Species

Human

11159-H08H截图.png

Alternate Names

ALPS5 CD CD152 CELIAC3 CTLA‑4 GRD4 GSE IDDM12

Background

Cytotoxic T‑lymphocyte protein 4, also known as CTLA4 and CD152, is a single‑pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7‑1) and CD86 (B7‑2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. CD152 or cytotoxic T lymphocyte antigen‑4 (CTLA‑4) is an essential receptor involved in the negative regulation of T cell activation. Because of its profound inhibitory role, CD152 has been considered a sound susceptible candidate in autoimmunity and a persuasive target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in the homeostasis and function of a population of suppressive cells, termed regulatory T cells (Treg).

Documents available on official page: Datasheet, COA, MSDS, Protocol, Reference citations.

CTLA4;CD152;CTLA4蛋白;CD152蛋白;CTLA4重组蛋白;

公司简介

北京义翘神州科技股份有限公司作为国家高新技术企业，主要从事生物试剂研发、生产、销售并提供技术服务的生物科技公司，主要业务包括重组蛋白、抗体、基因和培养基等产品，以及重组蛋白、抗体的开发和生物分析检测等服务，同时也为制药公司或者生物技术公司提供单克隆抗体候选药物的临床前规模生产服务。义翘神州拥有多项先进的核心技术以及从研发生产到放大生产的技术平台，为重组蛋白或者抗体试剂的高通量、高效率研发生产提供保障，旨在为全球制药企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。北京义翘神州是入选科技部"现代服务创新发展示范企业"的唯一的一家生物技术企业，是北京市民营企业科技创新百强，获批北京市单克隆抗体技术重点实验室，多次承担国家科技部重大新药创制专项、863科技攻关项目和北京市科委项目。

成立日期	(10年)
注册资本	12617.0632万人民币
员工人数	500人以上
年营业额	￥ 5000万-1亿
经营模式	试剂,定制,服务,实验室
主营行业	生物化工,生化试剂,抗体,蛋白组学,分子生物学