重组人白细胞介素-13蛋白

Recombinant Human IL13 Protein

Cat No: 10369‑HNAC｜Official product page:        https://cn.sinobiological.com/recombinant-proteins/human-il-13-10369-hnac

Specifications

Alternate Names

Background

Interleukin 13 (IL‑13) is a single‑chain glycosylated polypeptide, which belongs to the IL‑13/IL‑4 family. IL‑13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL‑13 exerts its effects through a multi‑subunit receptor comprising the alpha chain of the IL‑4 receptor (IL‑4Rα) and at least one of two known IL‑13‑specific binding chains (IL‑13 Rα1 and IL‑13 Rα2). As a cytokine, IL‑13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro‑inflammatory cytokines and chemokines, and thus down‑regulates macrophage activity. IL‑13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.