1-(4-乙基苯基)-2-(2H-1,2,3-三唑-4-基)乙-1-胺 | Novel Triazole Amine Building Block for Medicinal Chemistry 新品

1-(4-乙基苯基)-2-(2H-1,2,3-三唑-4-基)乙-1-胺 

是一种新颖的三唑类含胺药物化学砌块（Building Block），适用于创新药研发及早期药物发现。

该化合物同时含有 1,2,3-三唑杂环 和 一级胺官能团，可用于酰胺化、还原胺化、脲类构建等多种后续衍生化反应，为构建化合物库和开展 SAR（构效关系）研究提供了良好的结构基础。对位乙基苯环还能提供适度的疏水相互作用，有利于先导化合物优化。

适用方向：

• 药物化学（Medicinal Chemistry）

• SAR 构效关系研究

• 激酶抑制剂开发

• 肿瘤及中枢神经系统药物研发

• 新颖 Building Block 库构建

1-(4-Ethylphenyl)-2-(2H-1,2,3-triazol-4-yl)ethan-1-amine 

is a novel triazole-containing amine building block designed for medicinal chemistry and early-stage drug discovery.

The combination of a 1,2,3-triazole heterocycle with a primary amine provides a versatile scaffold for further functionalization through amide formation, reductive amination, urea synthesis, and other derivatization strategies. The para-ethylphenyl group introduces additional hydrophobic interactions that may enhance target binding during lead optimization.

This compound is suitable for:

• Medicinal chemistry programs

• Structure–activity relationship (SAR) studies

• Kinase inhibitor discovery

• CNS and oncology research

• Library synthesis and hit expansion

产品亮点（Highlights）

• Novel triazole-containing scaffold

• Versatile primary amine functionality

• Suitable for SAR exploration

• Ideal medicinal chemistry building block

• Available for custom synthesis and scale-up