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  • NQO2抗体—艾普蒂
  • NQO2抗体—艾普蒂
  • NQO2抗体—艾普蒂

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NQO2抗体—艾普蒂

Rabbit Polyclonal NQO2 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-21

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
NQO2抗体
英文名称：
Rabbit Polyclonal NQO2 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 5441 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
NQO2

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesQR2; DHQV; DIA6; NMOR2
WB Predicted band size26 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human NQO2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse kidney tissue and Mouse liver tissue lysates, Primary antibody: P10319(NQO2 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10319(NQO2 Antibody) at dilution 1/70. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10319(NQO2 Antibody) at dilution 1/70. (Original magnification: ×200)    


           

参考文献

以下是关于NQO2抗体的假设性参考文献示例(内容为模拟格式，具体文献需通过学术数据库查询验证)：

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1. **文献名称**：*The Role of NQO2 in Breast Cancer: Expression Analysis Using a Novel Polyclonal Antibody*

**作者**：Smith A, et al.

**摘要**：本研究开发了一种针对人源NQO2蛋白的多克隆抗体，并通过Western blot和免疫组化验证其特异性。研究发现，NQO2在乳腺癌组织中高表达，且与患者预后不良相关，提示其可能作为癌症治疗的潜在靶点。

2. **文献名称**：*Structural Characterization of NQO2 by Monoclonal Antibody-Based Immunoassays*

**作者**：Chen L, et al.

**摘要**：利用新开发的NQO2单克隆抗体，作者解析了NQO2在细胞内的亚定位(主要定位于细胞质)，并发现其与氧化应激反应中的关键蛋白存在相互作用，为理解NQO2的生物学功能提供了实验依据。

3. **文献名称**：*NQO2 as a Biomarker in Neurodegenerative Diseases: Insights from Immunohistochemical Staining*

**作者**：Wang X, et al.

**摘要**：通过商业化NQO2抗体对阿尔茨海默病患者脑组织进行染色，发现NQO2在淀粉样斑块周围异常聚集，提示其可能参与神经退行性病变的氧化损伤机制。

4. **文献名称**：*Development of a High-Affinity Antibody for NQO2 Inhibitor Screening*

**作者**：Kim H, et al.

**摘要**：研究团队报道了一种高灵敏度NQO2抗体的制备方法，并基于该抗体建立ELISA检测体系，用于筛选小分子抑制剂，为抗肿瘤药物开发提供了新工具。

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如需获取真实文献，建议在 **PubMed** 或 **Web of Science** 中搜索关键词：*NQO2 antibody*, *quinone reductase 2 immunodetection*，并筛选近年发表的实验研究类文章。

       

背景信息

The NAD(P)H:quinone oxidoreductase 2 (NQO2) antibody is a critical tool for studying the NQO2 enzyme, a member of the quinone oxidoreductase family. NQO2. also known as QR2. catalyzes the two-electron reduction of quinones, though unlike its homolog NQO1. it preferentially uses dihydrobiopterin (BH2) as a cofactor rather than NAD(P)H. This enzyme plays roles in detoxification, redox cycling, and cellular stress responses, with implications in oxidative damage, metabolic regulation, and disease pathogenesis. Dysregulation of NQO2 has been linked to cancer progression, neurodegenerative disorders (e.g., Alzheimer’s disease), and inflammatory conditions, making it a potential therapeutic target.

NQO2 antibodies enable the detection and quantification of NQO2 protein in tissues and cells via techniques like Western blotting, immunohistochemistry, and immunofluorescence. These antibodies are essential for investigating NQO2’s subcellular localization (primarily cytosolic and nuclear), expression patterns across different organs, and its interaction with substrates or inhibitors. Recent studies also explore NQO2’s role in metabolic reprogramming and its interplay with pathways like the Nrf2 antioxidant system. Validated antibodies are crucial for distinguishing NQO2 from structurally similar enzymes and ensuring specificity in experimental models. Ongoing research focuses on clarifying its dual roles in cytoprotection and cytotoxicity, influenced by cellular context and substrate availability.

       
NQO2抗体;NQO2;NQO2 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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