AKT1抗体

The AKT1 antibody is a crucial tool in studying the AKT1 protein, a serine/threonine kinase central to the PI3K/AKT/mTOR signaling pathway. AKT1 regulates cellular processes like proliferation, survival, metabolism, and apoptosis. Dysregulation of AKT1 is linked to cancers, diabetes, and neurological disorders, making it a key therapeutic target. AKT1 antibodies are designed to detect specific epitopes on AKT1. enabling researchers to analyze its expression, phosphorylation (e.g., at Thr308/Ser473 for activation), and localization in tissues or cell lines via techniques like Western blot, immunohistochemistry, and immunofluorescence. These antibodies help investigate AKT1's role in disease mechanisms, drug response, and signaling crosstalk. Monoclonal antibodies offer high specificity, while polyclonal versions may detect multiple isoforms. Validation across applications ensures reliability, supporting both basic research and clinical biomarker studies. AKT1 antibodies are pivotal in advancing precision medicine and understanding oncogenic pathways.