AUNP-12/1353563-85-5/抑制剂多肽AUNP-12；NP-12

Product Name：AUNP-12

CAS No.：1353563-85-5

Synonyms：抑制剂多肽AUNP-12；NP-12

Catalog No.：PYC-195

Description：AUNP-12 (NP-12) 是 PD-1 信号通路的一种多肽拮抗剂，是一种新型的免疫检查点调节剂，在抑制淋巴细胞增殖和效应功能方面对 PD-L1 和 PD-L2具有等效的拮抗作用。AUNP-12具有免疫激活作用、良好的抗肿瘤活性。AUNP-12由29个氨基酸组成，在赖氨酸的侧链上接了一个7个氨基酸的支链。

AUNP-12 (NP-12) is a peptide antagonist of the PD-1 signaling pathway and a novel immune checkpoint regulator that has equivalent antagonistic effects on PD-L1 and PD-L2 in inhibiting lymphocyte proliferation and effector function. AUNP-12 has immune activating effects and good anti-tumor activity. AUNP-12 consists of 29 amino acids, with a 7-amino acid side chain attached to the lysine side chain.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	SNTSESFK(SNTSESF)FRVTQLAPKAQIKE-NH2
Sequence(3-letter code)	H-Ser-Asn-Thr-Ser-Glu-Ser-Phe-Lys（Ser-Asn-Thr-Ser-Glu-Ser-Phe）-Phe-Arg-Val-Thr-Gln-Leu-Ala-Pro-Lys-Ala-Gln-Ile-Lys-Glu-NH2
Peptide Structure
Molecular Formula	C142H226N40O48
Molecular Weight	3261.55

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