磷酸核糖焦磷酸|T38472|TargetMol

Phosphoribosyl pyrophosphate pentasodium
108321-05-7

￥720 2mg 起订

上海更新日期：2024-09-30

TargetMol中国（陶术生物）

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产品详情:

中文名称：: 磷酸核糖焦磷酸

英文名称：: Phosphoribosyl pyrophosphate pentasodium

CAS号：: 108321-05-7

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

产品类别：: 抑制剂

货号：: T38472

Product Introduction

Bioactivity

名称	Phosphoribosyl pyrophosphate pentasodium
描述	Phosphoribosyl pyrophosphate (PRPP) pentasodium is a vital metabolite essential for the biosynthesis of purine and pyrimidine nucleotides, as well as the amino acids histidine and tryptophan. It also acts as a precursor for the important cofactors NAD and NADP.
体外活性	Phosphoribosyl diphosphate (PRPP) pentasodium is an important intermediate in cellular metabolism. PRPP is synthesized by PRPP synthase, as follows: ribose 5-phosphate + ATP → PRPP + AMP. PRPP is ubiquitously found in living organisms and is used in substitution reactions with the formation of glycosidic bonds. PRPP is utilized in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, the cofactors NAD and tetrahydromethanopterin, arabinosyl monophosphodecaprenol, and certain aminoglycoside antibiotics[1]. Phosphoribosyl diphosphate (5-Phosphoribosyl-l-pyrophosphate) pentasodium, a substrate shared by adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase, accumulates in human erythrocytes lacking hypoxanthine-guanine phosphoribosyltransferase. 5-Phosphoribosyl-l-pyrophosphate added to purified adenine phosphoribosyltransferase stabilizes it against heat inactivation[2].
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
关键字	Phosphoribosyl Pyrophosphate \| Phosphoribosyl pyrophosphate pentasodium

PRPPpentasodium|||磷酸核糖焦磷酸|TargetMol

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