化合物 Kobe2602|T1892|TargetMol

Kobe2602
454453-49-7

￥177 5mg 起订

￥321 10mg 起订

￥597 25mg 起订

上海更新日期：2024-09-30

TargetMol中国（陶术生物）

VIP3年

联系人：邵小姐

手机：4008200310 拨打

邮箱：marketing@tsbiochem.com

产品详情:

中文名称：: 化合物 Kobe2602

英文名称：: Kobe2602

CAS号：: 454453-49-7

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.39%

产品类别：: 抑制剂

货号：: T1892

Product Introduction

Bioactivity

Name	Kobe2602
Description	Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.
Kinase Assay	Migration assays: Assays are conducted in wells of a 24-well, 8 μm pore size Transwell plate. A 6.5-mm insert membrane is coated with 0.1 mL COL-I (300 μg/mL in MEGM) and then air dried for 16 hours. The collagen coating is rehydrated for 1 hour in 0.2 mL MEGM. The inner chamber contains MEGM-10% FBS as a chemoattractant. The compounds (10–100 μmol/L) or DMSO (0.1%–1%) are added to both inner and outer chambers. Before plating in the outer chamber, cells (5×104) are coincubated for 20 minutes with the compounds or DMSO in MEGM. Cells are allowed to migrate for 16 to 18 hours. The cells remaining on the top surface of the membrane are removed with a cotton swab. The cells on the bottom surface of the membrane are fixed and stained (0.2% crystal violet). The incorporated dye is extracted with 1% SDS and the A570 is measured.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 50 mg/mL (119.24 mM)
Keywords	H-Ras \| Inhibitor \| antiproliferative \| Kobe-2602 \| carcinoma \| Kobe 2602 \| inhibit \| Ras \| Kobe2602 \| Raf
Inhibitors Related	Dabrafenib \| CASIN \| Sorafenib tosylate \| PLX-4720 \| Regorafenib \| (S)-(-)-Perillyl alcohol \| RMC-6236 \| Sorafenib \| Sotorasib \| Regorafenib monohydrate \| MRTX1133 \| Ketoconazole
Related Compound Libraries	Inhibitor Library \| Bioactive Compound Library \| Anti-Cancer Active Compound Library \| Bioactive Compounds Library Max \| Anti-Colorectal Cancer Compound Library \| Kinase Inhibitor Library \| GPCR Compound Library \| Membrane Protein-targeted Compound Library \| Pain-Related Compound Library \| Anti-Prostate Cancer Compound Library

Kobe2602|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期	(12年)
注册资本	566.265100万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,工厂,试剂,定制,服务
主营行业	天然产物,生化试剂,分子生物学,分子砌块,生物技术服务