含羞草素|T6569|TargetMol

Mimosine
500-44-7

￥617 100mg 起订

￥415 50mg 起订

￥255 25mg 起订

上海更新日期：2024-09-30

TargetMol中国（陶术生物）

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联系人：邵小姐

手机：4008200310 拨打

邮箱：marketing@tsbiochem.com

产品详情:

中文名称：: 含羞草素

英文名称：: Mimosine

CAS号：: 500-44-7

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.84%

产品类别：: 抑制剂

货号：: T6569

Product Introduction

Bioactivity

Name	Mimosine
Description	L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
Cell Research	Cell proliferation in response to L-mimosine is measured using a [3H]thymidine incorporation assay. In this assay, 1 × 104 cells are cultured in each well of a 12-well plate in RPMI-1640 medium with 10% FCS and different concentrations (0–800 μM) of L-mimosine. After the required incubation periods (24 and 48 h), 0.5 μCi/ml of [3H]thymidine is added to each well of the 12-well plate. The cells are then incubated at 37°C in a humidified 5% CO2 atmosphere for 4 h. Cells are then washed twice with cold phosphate-buffered saline (PBS) and then with cold 5% trichloroacetic acid. Cells are lysed by adding 0.5 ml of 0.5 N NaOH. Then 400 μl of the solubilized cell solution are mixed with 4 ml of scintillation cocktail and counted in a liquid scintillation analyzer . Each sample was tested in quadruplicate.(Only for Reference)
In vitro	L-Mimosine 在PC-3细胞中阻断细胞周期的G1期，在LNCaP细胞中阻断S期，因此抑制了细胞增殖。[1] 作为脯氨酸羟化酶(PHD)抑制剂的L-Mimosine，可以刺激VEGF的产生，并在源自牙髓的细胞中增加它们的促血管生成能力。[2]
In vivo	L-mimosine (50 mg/kg i.p.) 在 Sprague-Dawley 大鼠中明显上调肾脏中的 HIF-1alpha 表达，并显著增强对肾灌注压的利尿反应。[3]
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 0.01 mg/mL (0.05 mM) H2O : < 1 mg/mL (insoluble or slightly soluble)
Keywords	anti-fibrosis \| Fe(III) \| NSC-69188 \| Anti-cancer \| herbicida \| inhibit \| Apoptosis \| iron-binding \| Mimosine \| NSC69188 \| insecticidal \| chelator \| antioxidant \| 含羞草碱 \| antiinflammation \| Inhibitor \| anti-influenza \| anti-virus \| 含羞草酸
Related Compound Libraries	Bioactive Compound Library \| Bioactive Compounds Library Max \| Selected Plant-Sourced Compound Library \| Alkaloid Natural Product Library \| Anti-Aging Compound Library \| Anti-Tumor Natural Product Library \| Natural Product Library \| Traditional Chinese Medicine Monomer Library \| Anti-Inflammatory Traditional Chinese Medicine Compound Library \| Natural Product Library for HTS

含羞草素|||NSC 69188|||L-Mimosine|||Leucenol|||Leucenine|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

成立日期	(12年)
注册资本	566.265100万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,工厂,试剂,定制,服务
主营行业	天然产物,生化试剂,分子生物学,分子砌块,生物技术服务