15-keto-17-phenyl trinor Prostaglandin F2α|T37934|TargetMol

15-keto-17-phenyl trinor Prostaglandin F2α
949564-89-0

￥1620 1mg 起订

￥12600 10mg 起订

￥6960 5mg 起订

上海更新日期：2025-11-17

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产品详情:

中文名称：: 15-keto-17-phenyl trinor Prostaglandin F2α

英文名称：: 15-keto-17-phenyl trinor Prostaglandin F2α

CAS号：: 949564-89-0

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

产品类别：: 抑制剂

货号：: T37934

Product Introduction

Bioactivity

名称	15-keto-17-phenyl trinor Prostaglandin F2α
描述	Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compound, 15-keto PGs still retain the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto Latanoprost (15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester) is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type PGs; for example, PGF2α will produce this degree of miosis at a dose of less than 1 μg/eye.
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	PBS (pH 7.2) : 2.5 mg/mL (6.47 mM), Sonication is recommended. DMF : 30 mg/mL (77.62 mM), Sonication is recommended. DMSO : 25 mg/mL (64.69 mM), Sonication is recommended. Ethanol : 30 mg/mL (77.62 mM), Sonication is recommended.
关键字	15-keto-17-phenyl trinor Prostaglandin F2a \| 15 keto 17 phenyl trinor Prostaglandin F2α \| 15-keto-17-phenyl trinor Prostaglandin F-2α \| 15keto17phenyl trinor Prostaglandin F2α \| 15-keto-17-phenyl trinor Prostaglandin F2alpha
相关产品	Evodiamine \| Rutin \| Lornoxicam \| p-Hydroxycinnamic acid \| Ethamsylate \| Tranilast \| Ufenamate \| Angoroside C \| Ozagrel \| Amtolmetin guacil \| Tetrahexyldecyl ascorbate \| Pranoprofen

15-keto-17-phenyl trinor Prostaglandin F2α|TargetMol

TargetMol Chemicals Inc. 总部位于马萨诸塞州波士顿，致力于为全球生化领域科学家的研究提供专业的产品和服务。TargetMol?品牌的客户群分布于40多个国家和地区，已发展成为全球知名的化合物库和小分子化合物研究供应商。 TargetMol?可提供160多种满足不同需求的化合物库，以及多种类型的生化试剂产品，包括12000多种抑制剂、16000多种天然产物和各类多肽、抗体、生命科学试剂盒等，此外，我们还建设有CADD（计算机辅助药物设计）研究中心、药理实验室、药化合成平台三大技术中心，全方位满足客户的定制需求。凭借我们优质的产品和服务、快速高效的全球供应链和专业的技术支持，我们将有效帮助您缩短研发周期，取得更成功的结果。

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