醉茄素A|T5687|TargetMol

WITHAFERIN A
5119-48-2

￥1080 1mg 起订

￥3230 5mg 起订

￥4630 10mg 起订

上海更新日期：2024-09-24

TargetMol中国（陶术生物）

VIP12年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 醉茄素A

英文名称：: WITHAFERIN A

CAS号：: 5119-48-2

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.83%

产品类别：: 抑制剂

货号：: T5687

Product Introduction

Bioactivity

Name	WITHAFERIN A
Description	WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer.
Cell Research	L929sA cells were co-treated with WITHAFERIN A and DTT for 1 h, and then TNF-induced NFκB activation was examined.
Animal Research	Mice are injected subcutaneously with zymosan in the footpad, and swelling is determined at several time points after the injection. Pretreatment with WITHAFERIN A(intraperitoneal) was performed to evaluate anti-inflammatory effects, whereas DEX (intraperitoneal) was chosen as a positive control. the mean of the differences between the zymosan-treated and untreated footpad for all the three groups. Both DEX.
In vitro	WITHAFERIN A 有效抑制了NFkappaB的激活，它通过一个对硫醇烷基化敏感的氧化还原机制，阻止了肿瘤坏死因子诱导的IkappaB激酶β的激活。
In vivo	WITHAFERIN A在体内显示抗炎性质——因为NFκB是炎症信号通路中的关键参与者，且WITHAFERIN A能抑制NFκB的激活。
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 27.5 mg/mL (58.44 mM)
Keywords	NF-κB \| Nuclear factor-κB \| WITHAFERIN A \| Inhibitor \| Ferroptosis \| Nuclear factor-kappaB \| inhibit
Inhibitors Related	L-Cystine \| Lidocaine hydrochloride \| Coenzyme Q10 \| Diallyl disulfide \| Glucosamine \| L-Glutamic acid monosodium salt \| Curcumin \| α-Vitamin E \| Sorafenib \| Indole-3-carbinol \| TBHQ \| Diethylmaleate
Related Compound Libraries	Inhibitor Library \| Anti-Cancer Active Compound Library \| Bioactive Compound Library \| Bioactive Compounds Library Max \| Selected Plant-Sourced Compound Library \| Anti-Tumor Natural Product Library \| Anti-Aging Compound Library \| Natural Product Library \| Anti-Inflammatory Traditional Chinese Medicine Compound Library \| Natural Product Library for HTS

醉茄素A|||醉茄素 A|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子