尿苷三乙酸酯|T21327|TargetMol

Uridine triacetate
4105-38-8

￥123 50mg 起订

￥163 100mg 起订

￥226 200mg 起订

上海更新日期：2024-09-24

TargetMol中国（陶术生物）

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邮箱：marketing@targetmol.com

产品详情:

中文名称：: 尿苷三乙酸酯

英文名称：: Uridine triacetate

CAS号：: 4105-38-8

品牌：: TargetMol

产地：: 美国

保存条件：: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.94%

产品类别：: 抑制剂

货号：: T21327

Product Introduction

Bioactivity

Name	Uridine triacetate
Description	Uridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized in the research of 5-fluorouracil (5-FU) and capecitabine toxicity, particularly targeting early-onset cardiac or central nervous system (CNS) complications.
In vitro	Uridine triacetate inhibits [3H]uridine uptake in ENT1 and ENT2 overexpressed HeLa cells, with IC50s of 28.4 μM and 228.4 μM respectively[4].
In vivo	Uridine triacetate (2 g/kg, oral gavage, every 8 h for 15 total doses) improves survival and reduced toxicity in 5-FU overdose mice. Uridine triacetate (2 g/kg, oral gavage, every 8 h for 15 total doses) improves survival and reduced 5-FU toxicity in DPD deficiency mice[3].
Storage	store at low temperature,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	H2O : Insoluble DMSO : 90 mg/mL (243 mM)
Keywords	RG 2133 Triacetate \| Uridine Triacetate \| RG2133 Triacetate \| Uridine \| RG-2133 Triacetate
Related Compound Libraries	Anti-Cancer Approved Drug Library \| Bioactive Compound Library \| Anti-Cancer Active Compound Library \| Anti-Cancer Compound Library \| Bioactive Compounds Library Max \| Approved Drug Library \| Clinical Compound Library \| Drug Repurposing Compound Library \| Anti-Cancer Clinical Compound Library \| Anti-Cancer Drug Library

尿苷三乙酸酯|||Tri-O-acetyluridine|||RG2133 triacetate|||RG-2133|||RG2133|||RG 2133 triacetate|||RG 2133|||PN-401|||PN401|||PN 401|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子