Tau重组蛋白，ACROBiosystems百普赛斯

Tau产品信息

英文名称：Microtubule-associated protein tau

中文名称：微管相关蛋白tau

靶点别称：TAU,DDPAC,FTDP-17,MAPT,MSTD,MTBT1,PHF-tau

物种：Human

属性：Protein / Cell

标记：Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

Tau分子背景

Tau是一种微管相关蛋白，由位于染色体17q21上的MAPT基因编码。Tau促进微管组装和稳定性，可能参与神经元极性的建立和维持。tau蛋白的过度磷酸化（tau内含物，pTau）可导致成对螺旋丝和直丝缠结的自组装，这与阿尔茨海默病、额颞叶痴呆和其他tau病的发病机制有关。

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