原阿片碱|T3429|TargetMol

Protopine
130-86-9

￥290 20mg 起订

上海更新日期：2024-09-23

TargetMol中国（陶术生物）

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产品详情:

中文名称：: 原阿片碱

英文名称：: Protopine

CAS号：: 130-86-9

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

纯度规格：: 99.45%

产品类别：: 抑制剂

货号：: T3429

Product Introduction

Bioactivity

Name	Protopine
Description	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
Kinase Assay	HT1080 cells are seeded in 24-well plates (2×104 cells per well) and treated with Dorsomorphin in the presence or absence of glucose or 10 mM 2DG for 2 h. HT1080 cells that overexpressed the wild-type and dominant negative AMPKα1 are prepared by transfecting plasmid DNA (pAMPKα1-wt, pAMPKα1-D168A and pcFlag as a control) in 6-well plates, seeding in 24-well plate and treating with UPR inhibitors. Cells are lysed with cell lysis buffer (20 mM Tris-HCl, pH 7.5, 250 mM NaCl, 10% glycerol, 0.5% NP-40, 1 mM EDTA, 1 mM EGTA, 0.2 mM PMSF, 1 μg/mL pepstatin, 0.5 μg/mL leupeptin, 5 mM NaF, 2 mM Na3Vo4, 2 mM β-glycerophosphate, 1 mM DTT). Relative AMPK kinase activity (mean±SD of duplicate determinations) to control sample (vehicle or pcFlag under normal growth conditions) is determined using the CycLex AMPK kinase assay kit[2].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 3.53 mg/mL (10 mM), Sonication is recommended. Chloroform 1:15 : Soluble
Keywords	Reactive Oxygen Species \| Inhibitor \| inhibit \| Protopine
Inhibitors Related	Lycopene \| Famotidine \| Meclizine dihydrochloride \| Coenzyme Q10 \| Alginic acid \| Sodium Thiocyanate \| Glucosamine \| 3-Amino-1,2,4-triazole \| α-Vitamin E \| Imeglimin hydrochloride \| L-Ascorbic acid \| Naringenin
Related Compound Libraries	Bioactive Compound Library \| Selected Plant-Sourced Compound Library \| Bioactive Compounds Library Max \| Ancient Chinese Classical Formulas Compound Library \| Anti-Aging Compound Library \| Traditional Chinese Medicine Monomer Library \| Membrane Protein-targeted Compound Library \| Anti-Inflammatory Traditional Chinese Medicine Compound Library \| Terpene Natural Product Library \| Natural Product Library for HTS

原阿片碱|||Macleyine|||Hypercorine|||Fumarine|||Corydinine|||Biflorine|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(12年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子