乙酰半胱氨酸|T0875

Acetylcysteine
616-91-1

￥326 500mg 起订

上海更新日期：2026-01-06

TargetMol中国（陶术生物）

VIP13年

联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 乙酰半胱氨酸

英文名称：: Acetylcysteine

CAS号：: 616-91-1

品牌：: TargetMol

产地：: 美国

保存条件：: keep away from moisture,The compound is unstable in solution. Please use soon | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.

纯度规格：: 99.95%

产品类别：: 抑制剂

货号：: T0875

Product Introduction

Bioactivity

名称	Acetylcysteine
描述	Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity.
细胞实验	For survival experiments, washed cells are resuspended in RPM1 1640 medium and plated in 0.5 mL at a density of 8-10×105 per well in 24 well plastic culture dishes coated with rat tail collagen. To feed, but to avoid loss of floating cells, fresh medium (0.2 mL) is added to the cultures on days 1, 5, and 10. For experiments involving 'primed' PC12 cells, cultures are pretreated for l-2 weeks with NGF in RPM1 1640 medium supplemented with 1% heat-iN-acetylcysteinetivated horse serum. The cells are then washed and passaged into serum-free RPM1 1640 medium.
动物实验	Rats are randomly allocated into five groups: sham group (n=5), control group with IIR (n=8) and three groups with IIR who are given N-acetylcysteine in different dosages: 150 mg/kg intraperitoneally 5 min before ischemia (n=8, group N-acetylcysteine 150), 300 mg/kg i.p 5 min before ischemia (n=7, group N-acetylcysteine 300), and 150 mg/kg i.p 5 min before ischemia plus 150 mg/kg 5 min before reperfusion (n=7, group N-acetylcysteine 150 + 150). After 4 h of reperfusion, the animals are euthanized by exsanguination from the abdominal aorta.[1]
体外活性	方法：人膀胱癌细胞 T24 用 Acetylcysteine (5-50 mM) 处理 24 h，使用 MTT 方法检测细胞活力。结果：Acetylcysteine 剂量依赖性抑制 T24 细胞活力，IC50 为 33.33 mM。[1] 方法：大鼠心肌细胞 H9c2 用 Acetylcysteine (2-4 mM) 处理 12-24 h，使用 Flow Cytometry 方法检测细胞凋亡情况。结果：Acetylcysteine 剂量和时间依赖性诱导 H9c2 细胞凋亡。[2]
体内活性	方法：为研究对小鼠凋亡性肝损伤的影响，将 Acetylcysteine (150 mg/kg) 单次腹腔注射给 CD-1 小鼠，30 min 后使用 GalN/LPS 诱导肝损伤。结果：Acetylcysteine 预处理显著减轻了 GalN/LPS 诱导的肝细胞凋亡。Acetylcysteine 通过其强大的 ROS 清除和抗凋亡作用减轻 GalN/LPS 诱导的凋亡性肝损伤。[3] 方法：为检测体内活性，将 Acetylcysteine (500 mg/kg) 口服给药给亨廷顿舞蹈症 (HD)的 R6/1 转基因小鼠，每天一次，持续九周。结果：慢性 Acetylcysteine 给药延迟了 R6/1 小鼠运动缺陷的发生和发展，同时对 R6/1 和野生型小鼠都具有抗抑郁样作用。[4]
存储条件	keep away from moisture,The compound is unstable in solution. Please use soon \| Powder: -20°C for 3 years \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	DMSO : 60 mg/mL (367.67 mM), The compound is unstable in solution, please use soon. Ethanol : 31 mg/mL (189.96 mM), Sonication is recommended. H2O : 100 mg/mL (612.78 mM), Sonication and heating are recommended. 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 2.5 mg/mL (15.32 mM), Sonication is recommeded.
关键字	TNF-α \| ROS \| ReactiveOxygenSpecies \| Reactive Oxygen Species \| Inhibitor \| inhibit \| InfluenzaVirus \| Influenza Virus \| Ferroptosis \| EndogenousMetabolite \| Endogenous Metabolite \| Apoptosis \| Acetylcysteine
相关产品	Glycerol \| Aceglutamide \| Levulinic acid \| Emtricitabine \| L-Pyroglutamic acid \| D-(+)-Trehalose dihydrate \| Sucrose \| Hemin \| Gluconate Calcium \| Thymidine \| D(+)-Raffinose pentahydrate \| Ethyl linoleate

易咳净|||乙酰半胱氨酸|||N-Acetyl-L-cysteine|||N-Acetylcysteine|||N-Acetyl Cysteine|||NAC|||LNAC|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(13年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子