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  • 车叶草苷|T3847

车叶草苷|T3847

Asperuloside
14259-45-1
2470.00 50瓶 起订
927.00 10瓶 起订
219.00 1瓶 起订
555.00 5瓶 起订
1650.00 25瓶 起订
上海 更新日期:2024-12-02

TargetMol中国(陶术生物)

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联系人:邵小姐
电话:021-021-33632979拨打
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邮箱:marketing@targetmol.com

产品详情:

中文名称:
车叶草苷
英文名称:
Asperuloside
CAS号:
14259-45-1
品牌:
TargetMol
产地:
美国
保存条件:
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
纯度规格:
99.42%
产品类别:
抑制剂
货号:
T3847

Product Introduction

Bioactivity

名称Asperuloside
描述Asperuloside (Asperulosid) has anti-inflammatory activity.
激酶实验The chemiluminescent assay is used to confirm PCSEE MAO-A and MAO-B inhibitory effects and to test BNN and BVN hMAO-A and hMAO-B inhibition using MAO-Glo kit. Each enzyme's Arbitrary Light Unit (ALU) is measured in the presence of PCSEE, BNN, BVN, and standard DEP as an MAO-BI positive control. Briefly, hMAO-A and hMAO-B isozymes are diluted to 2× with reaction buffer (pH 7.4) and preincubated with 4× PCSEE, BNN, BVN, or DEP working solutions at RT for 30?min in white opaque 96-well plates. For determining activity inhibition, final 8.5?μg/mL concentrations of PCSEE, BNN, BVN, and DEP are used. For IC50 determination, 8× PCSEE and BNN working solutions are serially diluted using reaction buffers (pH 7.4) to make a 4× concentration. Ten points' range of PCSEE (1.0 to 250.0?μg/mL) and BNN (up to 400?μM (135.4?μg/mL)) final concentrations is used. Controls used are with and without ethanol. Ethanol solvent in controls is kept to a maximum final (volume) of ≤2%. Each isozyme is substituted with the reaction buffer for the blank. Based on our preliminary optimizations and Valley's method, the reaction is initiated by adding 4× luciferin derivative substrate (LDS) for a final (concentration) of 40 and 4?μM for hMAO-A and hMAO-B reactions, respectively. The final volume per well of each reaction is 50?μL. The reaction is optimized for the amount of A and B enzyme used to be incubated for less than 3.5?h at RT. To stop the reaction and produce the luminescence signal RLDR is added to all wells, 50?μL to each well, and incubated for a further 30?min.
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 60 mg/mL (144.8 mM)
关键字Inhibitor | NO Synthase | NOS | Nitric oxide synthases | Asperuloside | inhibit
相关产品2,4-Diamino-6-hydroxypyrimidine | Mifepristone | Methylene Blue trihydrate | Ethyl cinnamate | L-Arginine hydrochloride | S-Methylisothiourea sulfate | L-Arginine | Aminoguanidine hydrochloride | L-NAME hydrochloride | Nitroarginine
相关库经典已知活性库 | 已知活性化合物库 | 古代经典名方目录分子库 | 苗药化合物库 | 药食同源库 | 抗衰老化合物库 | 中药单体化合物库 | 天然产物库 | 萜类天然产物库 | 中药抗炎分子库
Asperulosid|||车叶草苷

公司简介

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起,为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部,化学事业部,生物事业部和新材料部。 从虚拟筛选到实体化合物分子供应;从商业化产品销售到个性化定制合成;从对明确靶点的分子筛选到对明确分子的多靶点筛选,从高通量筛选到化学结构优化,我们都可以满足您的科研用品及技术服务的需求。 经过在中国市场五年的精心耕耘,我们已成为筛选化合物领域优秀的供应商,为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期 (12年)
注册资本 566.2651万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,试剂,定制,服务
主营行业 化学试剂,生物活性小分子

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