CD59蛋白-ACROBiosystems百普赛斯

CD59产品信息

英文名称：CD59 glycoprotein

中文名称：CD59糖蛋白

靶点别称：CD59

物种：Human

属性：Protein

标记：Biotin-labeled/Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

>95% as determined by SDS-PAGE.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

CD59分子背景

CD59，也称为膜攻击复合物抑制因子（MACIF）、保护蛋白、1F5抗原、HRF-20和MIRL。CD59已被鉴定为一种糖基磷脂酰肌醇锚定的膜蛋白，作为膜攻击复合物质形成的抑制剂，调节补体激活。补体膜攻击复合物（MAC）作用的强效抑制剂。通过与组装MAC的C8和/或C9互补物结合起作用，从而防止完全形成渗透压孔所需的C9多拷贝的掺入。这种抑制剂似乎具有物种特异性。参与与蛋白酪氨酸激酶复合的T细胞活化的信号转导。