Anti-CD59antibody-CD59重组兔单克隆抗体

Host:Rabbit

Target Protein:CD59

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:966

Swiss Prot:P13987

Source:KLH conjugated synthetic peptide derived from human CD59: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:50-1:100)
Flow-Cyt(1:100)

Cross Reactive Species:Human
.

本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！