aladdin 阿拉丁 E126609 依泽替米贝 163222-33-1 ≥99%

中文名：依泽替米贝

英文名：Ezetimibe

中文别名：Zetia|Ezetrol|依泽替米贝|(3R,4S)-1-(4-氟苯基)-3-[(S)-3-(4-氟苯基)-3-羟基丙基]-4-(4-羟基苯基)-2-氮杂环丁酮|依折麦布

英文别名：Ezetimibe|163222-33-1|Zetia|Ezetrol|Ezedoc|Sch 58235|SCH58235|(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one|SCH-58235|(-)-Sch 58235|ezetimiba|ezetimibum|UNII-EOR26LQQ24|(3R,4S)-1-(4-fluorophenyl)-

纯度：≥99%

货号：E126609

包装：5g、1g、25g

Cas号：163222-33-1

存储温度：-20°C储存

产品介绍：

Ezetimibe has been reported to be a cholesterol transport inhibitor. Mechanistic studies show that this compound directly affects Niemann-Pick C1-like 1 (NPC1L1) and prevents it from incorporating into clathrin-coated vesicles. NPC1L1 is a polytopic transmembrane protein that facilitates absorption of cholesterol via clathrin/AP2-mediated endocytosis. By binding to NPC1L1, ezetimibe prevents endocytosis of this protein therefore blocking cholesterol transfer across membranes. Ezetimibe is used clinically to lower plasma cholesterol levels.A cholesterol transport inhibitor that binds to NPC1L1

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