盐酸伊伐布雷定

盐酸伊伐布雷定中文同义词盐酸伊伐布雷啶;盐酸伊伐布雷定IVABRADINE(研发中);盐酸伊伐布雷定及中间体;盐酸伊伐布雷定(依法布雷定);依伐布雷定盐酸盐;盐酸依伐布雷定;盐酸伊伐布雷;盐酸伊伐布雷定/盐酸依法布雷定英文名称Ivabradinehydrochloride英文同义词IvabradineHCl;Ivabradinehydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-onehydrochloride;Ivabradinehydrochloride,>=99%;IVABRADINEHYDROCHLORIDE-OTHERCOMPOUNDSCONTAININGANUNFUSEDPYRAZOLERING(WHETHERORNOTHYDROGENATED)INTHESTRUCTUR;Ivabradinehydrochloride,98%,aIfinhibitor;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-oneHydrochloride;CorlentorCAS号148849-67-6分子式C27H37ClN2O5分子量505.05EINECS号638-798-3相关类别小分子抑制剂，天然产物;医药原料药;医药原料;医药中间体;原料药;小分子抑制剂;神经信号;细胞生物学试剂;心脏;药物杂质及中间体;原料;医药、农药及染料中间体;Intermediates&FineChemicals;Pharmaceuticals;API;ChiralReagents;Heterocycles;CardiovascularAPIs;Inhibitors;医药化工类;杂质对照品;化学试剂;临床检测标准物质Mol文件148849-67-6.mol结构式盐酸伊伐布雷定性质熔点193-196?C比旋光度58921+7.8°;36521+27.8°(c=1%inDMSO)储存条件2-8°C溶解度在水中的溶解度为≥5mg/mL（加热）形态粉末颜色白色至米色旋光性(opticalactivity)[α]/D+5to+9°,c=1inDMSOMerck14,5247InChIKeyHLUKNZUABFFNQS-ZMBIFBSDSA-NSMILESC([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl|&1:1,r|CAS数据库148849-67-6(CASDataBaseReference)盐酸伊伐布雷定用途与合成方法用途盐酸伊伐布雷定是首个选择性和特异性调节心率抑制剂,对窦房结有选择性作用而对心脏内传导、心肌收缩或心室复极化无作用。