aladdin 阿拉丁 S101540 血根碱水合物 5578-73-4 ≥97% (HPLC)

中文名：血根碱水合物

英文名：Sanguinarine chloride hydrate

中文别名：氯化血根碱

英文别名：SANGUINARINE CHLORIDE|5578-73-4|Sanguinarium Chloride|Viadent|Sanguinarine chloride hydrate|Sanguinarine hydrochloride|Sanguinarine (chloride)|[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-, chloride (1:1)|CHEMBL490129|5578-73-4 (c

纯度：≥97% (HPLC)

货号：S101540

包装：50mg、250mg

Cas号：5578-73-4

产品介绍：

Sanguinarine chloride is a benzophenanthridine alkaloid and potent, noncompetitive sodium/Potassium-ATPase Protein Inhibitors (Na+/K+ ATPase) inhibitor with anticancer properties. This product has been observed to induce apoptosis in cultured C6 rat glioblastoma cells potentially via a downregulative ability of extracellular singal-regulated and Akt signaling pathways. It is reported that sanguinarine also inhibits protein phosphatase 2C (PP2) and induces human promyelocytic leukemia cell line HL60 apoptosis throμgh the phosphorylation of p38, a PP2Cα substrate associated with caspase-3/7 activity. This compound posesses antimicrobial and anti-plaque qualities. Sanguinarine chloride is an inhibitor of MKP-1 and PP2. Isolated from the leaves and stems of Macleaya cordata and M. microcarpa.一个具有抗菌，消炎，抗氧化性能的天然产物。有抑制肿瘤细胞株扩增和促凋亡作用。 A benzophenanthridine alkaloid and potent, noncompetitive Na+/K+-and Mg2++-ATPase inhibitor

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