aladdin 阿拉丁 I423008 3-异丁基-1-甲基黄嘌呤(IBMX) 28822-58-4 10mM in DMSO

中文名：3-异丁基-1-甲基黄嘌呤(IBMX)

英文名：3-Isobutyl-1-methylxanthine

中文别名：IBMX|1-甲基-3-异丁基黄嘌呤

英文别名：IBMX|3-Isobutyl-1-methylxanthine|28822-58-4|isobutylmethylxanthine|Methylisobutylxanthine|1-METHYL-3-ISOBUTYLXANTHINE|1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-|3-Isobutyl-1-methyl-1H-purine-2,6(3H,7H)-dione|3-isobutyl-1-methylxanthine

纯度：10mM in DMSO

货号：I423008

包装：1ml

Cas号：28822-58-4

存储温度：-80℃储存

产品介绍：

IBMX is a widely-used non-specific inhibitor of cyclic AMP (cAMP) and cyclic GMP (cGMP) phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 μM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP levels, activating cyclic-nucleotide-regulated protein kinases. Methylxanthines, including IBMX, caffeine, and theophylline, bind adenosine receptors,typically antagonizing the suppressive effects of natural agonists.

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