aladdin 阿拉丁 U414262 UBCS039 358721-70-7 98%

中文名：UBCS039

英文名：UBCS039

纯度：≥98%

货号：U414262

Cas号：358721-70-7

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

UBCS039 UBCS039 is the first synthetic SIRT6 activator with EC50 of 38 μM,induces a time-dependent activation of autophagy in several human tumor cell lines.

Targets

SIRT6 (Cell-free assay) 38 μM(EC50)

In vitro

UBCS039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.UBCS039 leads to autophagosome accumulation and induces autophagic flux in human cancer cells.UBCS039 also induces autophagy-associated cell death.

Cell Research(from reference)

Cell lines：HeLa cells 

Concentrations：100\u2009µM 

Incubation Time：24\u2009h 

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