aladdin 阿拉丁 D413262 二甲啡烷磷酸盐 36304-84-4 98%

中文名：二甲啡烷磷酸盐

英文名：Dimemorfan phosphate

纯度：≥98%

货号：D413262

Cas号：36304-84-4

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Dimemorfan phosphate Dimemorfan (3,17-dimethylmorphinan) is a nonnarcotic antitussive drug, acting as a potent agonist of the σ1 receptor (Ki = 151 nM).

Targets

σ1 receptor (on rat brain membranes) 150 nM(Ki)

In vitro

Dimemorfan has a relative high affinity at sigma-1 (σ1) receptors (Ki=151 nM) vs sigma-2 receptors (Ki=4421 nM) as determined by receptor binding assay on rat brain membranes.

In vivo

Dimemorfan acts as a α1 receptor agonist to exhibit anti-amnesic effects against scopolamine- and β-amyloid peptide-(25-35)-induced memory impairments.

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