aladdin 阿拉丁 C104902 鹅去氧胆酸 474-25-9 98%

中文名：鹅去氧胆酸

英文名：Chenodeoxycholic acid

中文别名：鹅脱氧胆酸

英文别名：chenodeoxycholic acid|Chenodiol|474-25-9|Chenix|Chenic acid|Cdca|Chenodesoxycholic acid|Chenodeoxycholate|Gallodesoxycholic acid|Chendol|Anthropodeoxycholic acid|Anthropodesoxycholic acid|Anthropododesoxycholic acid|Chenofalk|Chenodesoxycholsaeure|Chenoco

纯度：98%

货号：C104902

包装：100g、25g、5g

Cas号：474-25-9

存储温度：2-8°C储存,避光

产品介绍：

Chenodeoxycholic Acid, Free Acid and its 7β-isomer ursodeoxycholic acid are potent (nanomolar affinity) selective inhibitors of DD2 (AKR1C2). These compounds were non-competitive inhibitors of AKR1D1 yielding Ki values of 3.2 μM for chenodeoxycholic acid. This chemical is a hydrophobic primary bile acid, which increases intracellular Ca2+ in rat hepatocyte couplets. Studies indicate that Chenodeoxycholic Acid induces apoptosis throμgh a PKC dependent pathway. It is known that Chenodeoxycholic Acid is essential in the metabolism of cholesterol via activation of nuclear receptors. This bile acid can also bind to BABP with a stoichiometery of 1:2. Alternate studies indicate that chenodeoxycholic acid can inhibit the expression of IL-6 and cell viability in QBC939 cells.An apoptosis inducer via PKC-dependent signalling pathway.

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