aladdin 阿拉丁 A412540 APX-115自由基 1270084-92-8 99%

中文名：APX-115自由基

英文名：APX-115 free base

纯度：Moligand™，≥99%

货号：A412540

Cas号：1270084-92-8

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

APX-115 free base (Ewha-18278 free base) is a potent, orally active inhibitor ofpan NADPH oxidase (pan-Nox)with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base (Ewha-18278 free base) significantly suppresses the expression of inflammatory molecules includingMCP-1/CCL2,IL-6, andTNFαin the diabetic kidney.

Targets

MCP-1/CCL2 ; IL-6 ; TNFα ; NOX2 (Cell-free assay); NOX4 (Cell-free assay) 33094,; 0.57 μM(Ki); 0.63 μM(Ki)

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