aladdin 阿拉丁 C129833 克拉屈滨 4291-63-8 ≥98%

中文名称：

克拉屈滨

英文名称：

Cladribine

CAS号：

4291-63-8

品牌：

阿拉丁

产地：

上海

保存条件：

2-8°C储存

纯度规格：

≥98%

产品类别：

生命科学 生化试剂

分子式：

C10H12ClN5O3

分子量：

285.69

MDL：

MFCD00153939

运输条件：

冰袋运输

用途：

It is a chlorinated purine nucleoside with activity against lymphoproliferative disorders, such as hairy cell leukemia (HCL) and multiple myeloma (MM). 2-CdA resists ADA degradation and is phosphorylated to CdATP in lymphocytes. CdATP incorporation into DNA induces strand breaks and the activation of apoptosis. 2-CdA may also be used in studies involving the inhibition of DNA polymerase(s). Cladribiane, like fludarabine, is a prodrug that is must be phosphorylated intracellularly to the monophosphate by the nuclear/cytosol enzyme deoxycytidine kinase (dCK) and possibly by the mitochondrial enzyme deoxyguanosine kinase (dGK).

产品规格：

100mg、10mg、50mg

货号：

C129833

是否进口：

否