aladdin 阿拉丁 I132661 靛玉红-3'-单肟 160807-49-8 ≥98%(HPLC)

中文名：靛玉红-3'-单肟

英文名：Indirubin-3′-oxime

英文别名：INDIRUBIN-3'-MONOXIME|indirubin-3'-oxime|160807-49-8|Indirubin-3-monoxime|indirubin-3-oxime|Indirubin-3monoxime|667463-82-3|3-[3-(Hydroxyamino)-1H-indol-2-yl]indol-2-one|Indirubin 3'-monoxime|CHEBI:43645|indirubin-3'-monooxime|(2Z,3E)-3-(Hydroxyimino)-[2,

纯度：≥98%(HPLC)

货号：I132661

包装：1mg、25mg、5mg

Cas号：160807-49-8

产品介绍：

Indirubin-3'-monoxime is a potent inhibitor of GSK-3β (IC50=22 nM)1. Indirubin-3'-monoxime also inhibits CDK1 (p34cdc2; IC50=180 nM) and CDK5 (IC50=100 nM)1. Indirubin-3'-monoxime reversibly arrests asynchronous HBL-100 cells at G22. This compound induces apoptosis in the mammary carcinoma cell line MCF-7 (10 μM). Indirubin-3'-monoxime is an inhibitor of Cdk2, cyclin A, cyclin B, cyclin E and p35.A potent inhibitor of GSK-3β, Cdk1, and Cdk5

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