多粘菌素B1/4135-11-9/Polymyxin B1

Product Name：Polymyxin B1

CAS No.：4135-11-9

Synonyms：多粘菌素B1

Catalog No.：218P440

Brand：HongTide（上海鸿肽生物）

Description：Polymyxin B1是一种有效的抗菌脂肽，衍生自多头芽孢杆菌，序列中含有较多的非天然氨基酸，并且包含环状结构。Polymyxin B1 是 Polymyxin B的主要成分。Polymyxin B1可以通过与细菌细胞膜的相互作用来诱导细菌细胞裂解。Polymyxin B1可用于多重耐药性革兰氏阴性菌感染的研究。

Polymyxin B1 is an effective antibacterial lipopeptide derived from Bacillus multiforme, with a sequence containing a large number of unnatural amino acids and a circular structure. Polymyxin B1 is the main component of Polymyxin B. Polymyxin B1 can induce bacterial cell lysis by interacting with bacterial cell membranes. Polymyxin B1 can be used for the study of multidrug-resistant Gram negative bacterial infections.

Purity (HPLC) ≥95.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	N2-[[(6S)-6-Methyloctanoyl]-A2bu-T-A2bu-cyclo(A2bu-A2bu-d-Phe-L-A2bu-A2bu-T-)
Sequence(3-letter code)	N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)
Peptide Structure
Molecular Formula	C56H98N16O13
Molecular Weight	1203.48

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