Anti-Phospho-Glycogen synthase 1 (Ser641) antibody-磷酸化葡萄糖合成酶1抗体

Rabbit  Anti-Phospho-Glycogen synthase 1 (Ser641) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Phospho-Glycogen synthase 1 (Ser641)

IR:Immunogen Range:PA(p-S)VP

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2997

Swiss Prot:P13807

Source:KLH conjugated Synthesised phosphopeptide derived from human Glycogen synthase 1 around the phosphorylation site of Ser641:PA(p-S)VP 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:2000-5000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Cat

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！