丽蝇抗病毒肽1/347884-61-1/Alloferon

Product Name：Alloferon

CAS No.：347884-61-1

Synonyms：Alloferon 1；Antimicrobial peptide；丽蝇抗病毒肽1

Catalog No.：218P378

Brand：HongTide（上海鸿肽生物）

Description：Alloferon是一类从细菌感染的果蝇分离得到的十三肽，具有抗肿瘤、抗病毒、抗炎症、免疫调控的多重生物活性，其发挥作用的机理类似免疫调节肽，通过激发机体自然杀伤细胞NK的细胞毒杀作用及促进干扰素INF-α来发挥其生物活性。2003年，Alloferon成功在俄罗斯上市，临床适应症为女性人乳头瘤病毒HPV感染。鉴于Alloferon的独特优势，如无细胞毒性、无免疫原性、无突变或致癌效应、无胚胎毒性、无生殖毒性，对于其衍生物的研究将为创造出更高效、安全的抗菌肽AMP、抗肿瘤多肽ACP。

Alloferon is a kind of thirteen peptides isolated from bacterial infected Drosophila melanogaster, which has multiple biological activities of anti-tumor, anti-virus, anti-inflammatory, and immune regulation. Its mechanism of action is similar to that of immune regulatory peptides. It can stimulate the cytotoxicity of Natural killer cell NK and promote interferon INF- α To exert its biological activity. In 2003, Alloferon was successfully launched in Russia, with a clinical indication of female human papillomavirus HPV infection. In view of the unique advantages of Alloferon, such as no cytotoxicity, no immunogenicity, no mutation or carcinogenic effect, no embryotoxicity, no Reproductive toxicity, the research on its derivatives will create more efficient and safe Cathelicidin AMP and anti-tumor polypeptide ACP.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	HGVSGHGQHGVHG
Sequence(3-letter code)	H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH
Peptide Structure
Molecular Formula	C52H76N22O16
Molecular Weight	1265.32

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