拮抗剂多肽Fz7-21/2247635-23-8/鸿肽生物多肽合成

Product Name：Fz7-21

CAS No.：2247635-23-8

Synonyms：拮抗剂多肽Fz7-21

Catalog No.：218P101

Brand：HongTide（上海鸿肽生物）

Description：Fz7-21是一种FZD7（FZD7）受体的肽拮抗剂，由14个氨基酸组成，肽链的两端均被封闭，选择性地与FZD7-CRD亚类结合。人和小鼠FZD7-CRD的EC50值分别为58和34nm。Fz7-21在外源性WNT3A（IC50=100 nM）刺激或转染表达WNT3A或WNT1的HEK293细胞中削弱Wnt/β-catenin信号传导。小鼠β2 1-3nM细胞的稳定化作用。

Fz7-21 is a peptide antagonist of the FZD7 (FZD7) receptor, composed of 14 amino acids, with both ends of the peptide chain blocked and selectively binding to the FZD7-CRD subclass. The EC50 values of human and mouse FZD7-CRD were 58 and 34 nm, respectively. Fz7-21 attenuates Wnt in HEK293 cells expressing WNT3A or WNT1 stimulated or transfected with exogenous WNT3A (IC50=100 nM)/ β- Catenin signal transduction. mice β The stabilization effect of 2 1-3nM cells.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

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