EDTA Na2 乙二胺四乙酸二钠　

Product Number: CS6323

CAS Number: 6381-92-6

Storage Temperature Room Temperature

Product Description:

Appearance: White crystalline powder

Molecular formula: C₁₀H₁₄N₂O₈Na₂ž2H₂O

Molecular weight: 372.24

Purity:≥ 99.0%

EDTA is an inhibitor of metalloproteases and metal-activated proteases, at effective concentrations of 1-10μM. The product acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA may interfere with biological processes which are metal-dependent.

For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. Using a 2% EDTA solution, 1-2 drops per ml of whole blood can be used as an anticoagulant.

Preparation Instructions:

This product is slowly soluble in water at room temperature up to 0.26 M, which is approximately 96mg in a final volume of 1 ml. The pH of this solution will be in the range of 4 to 6. EDTA salts are more soluble in water as the pH increases: the more EDTA there is in the salt form, the higher the pH of a water solution, and therefore, the higher the room temperature solubility. This can be achieved by a gradual addition of concentrated sodium hydroxide solution to the EDTA solution.

Storage/Stability:

A stock solution of 0.5 M EDTA in water (pH 8.5) is stable for months at 4 °C. Solutions of EDTA may be autoclaved.

Precautions and Disclaimer:

For Laboratory Use Only. Not for drug, household or other uses.