基本信息 产品详情 公司简介 推荐产品
网站主页 化工产品目录 生物化工 抑制剂 细胞骨架(Cytoskeletal Signaling) HSP e.g. HSP90 激活剂 伊利司莫 Elesclomol (STA-4783)
  • 488832-69-5Elesclomol (STA-4783)

488832-69-5Elesclomol (STA-4783)

Elesclomol (STA-4783)
488832-69-5
询价 1盒 起订
上海 更新日期:2024-08-09

上海一研生物科技有限公司

VIP2年
联系人:吴菲
电话:021-69985186拨打
手机:13611928337 拨打
邮箱:3427709316@qq.com

产品详情:

中文名称:
Elesclomol (STA-4783)
英文名称:
Elesclomol (STA-4783)
CAS号:
488832-69-5
品牌:
一研
保存条件:
Store at -20°C
产品类别:
抑制剂
Cas:
488832-69-5

产品属性:

产品名称

规格

CAS

型号

Elesclomol (STA-4783)

10mM (in 1mL DMSO) 5mg 10mg 50mg 200mg

488832-69-5

EY-Y0164746

Cas No.488832-69-5

别名 STA 4783, STA4783

化学名 1-N',3-N'-bis(benzenecarbonothioyl)-1-N',3-N'-dimethylpropanedihydrazide

分子式 C19H20N4O2S2

Elesclomol (STA-4783).png

分子量 400.5

溶解度 20.15mg/mL in DMSO, 5.68 mg/mL in EtOH with ultrasonic and warming

储存条件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
Elesclomol (also known as STA-4783), originally identified in a cell-based phenotypic screen for proapoptotic activity, is a novel small-molecule that potently induces apoptosis of cancer cells through the rapid generation of reactive oxygen species (ROS) and the induction of unmanageable levels of oxidative stress. Elesclomol exhibits autitumor activity against a broad spectrum of types of cancer cell in human tumor xengograft models due to its excessive ROS production and elevated levels of oxidative stress leading to the death of cancer cells.  Elesclomol is currently being studies as a novel cancer therapeutic, in which it has demonstrated ability to prolong progression-free survival in study subjects.

Reference

[1].Ronald K. Blackman, Kahlin Cheung-Ong, Marinella Gebbia, David A. Proia, Suqin He, Jane Kepros, Aurelie Jonneaux, Philippe Marchetti, Jerome Kluza, Patricia E. Rao, Yumiko Wada, Guri Giaever, Corey Nislow. Mitochondrial electron transport is the cellular target of the oncology drug elesclomol. PLoS ONE 2012; 7(1): e29798

[2].Jessica R. Kirshner, Suqin He, Vishwasenani Balasubramanyam, Jane Kepros, Chin-Yu Yang, Mei Zhang, Zhenjian Du, James Barsoum, and John Bertin. Elesclomol induces cancer cell apoptosis through oxidative stress. Mol Cancer Ther 2008; 7:2319-2327


488832-69-5;C19H20N4O2S2;Elesclomol (STA-4783;

公司简介

上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业,公司自成立以来,秉承""全心全意服务于科研工作者""的企业理念,立足生物科技领域,运用生物技术和科研试剂,发展现代生物科技,为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品,服务生物科技领域的科学研究人员。 公司具有对普通货物、冷藏及冷冻仓库的存储、包装及运输能力。 公司将始终坚持信誉立业、以人为本、质量保证、诚信服务的宗旨,不断拼搏,开拓进取,与各界朋友携手共创美好未来。

成立日期 (11年)
注册资本 100
员工人数 50-100人
年营业额 ¥ 100万以内
经营模式 工厂,试剂
主营行业 生化试剂,抗体,细胞培养,分子生物学,免疫安全

Elesclomol (STA-4783)相关厂家报价

  • 伊利司莫
  • 伊利司莫
  • 上海和宁美生物医药科技有限公司 VIP
  • 2024-07-08
  • 询价
  • Elesclomol
  • Elesclomol
  • 上海芮晖化工科技有限公司 VIP
  • 2024-06-17
  • 询价
内容声明
拨打电话 立即询价