中文名称

N-[（1S，2R，3E）-2-羟基-1-（羟甲基）-3-十七碳烯-1-基]-辛酰胺； N-辛酰基鞘氨醇； C-8神经酰胺

英文名字

N-[（1S，2R，3E）-2-hydroxy-1-（hydroxymethyl）-3-heptadecen-1-yl]-octanamide； N-octanoylsphingosine； C-8 Ceramide

供应商

开曼生物

产品货号

62540-10

背景资料

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide， it is metabolized within cells to generate natural ceramides， often causing a dramatic increase in cellular ceramide levels. For this reason， treatment of cells with C-8 ceramide may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C-8 ceramide likely mediates many diverse biological activities， as do natural ceramides. It promotes the differentiation of human keratinocytes and induces apoptosis of both human leukemia cells and the U937 cell line.

产品描述

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide， it is metabolized within cells to generate natural ceramides， often causing a dramatic increase in cellular ceramide levels.{5258} For this reason， treatment of cells with C-8 ceramide may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C-8 ceramide likely mediates many diverse biological activities， as do natural ceramides. It promotes the differentiation of human keratinocytes{5185} and induces apoptosis of both human leukemia cells and the U937 cell line.{5258，4667}

保存建议

建议您在收到开曼生物品牌的C-8 Ceramide （10 mg）产品后置于-20度保存，产品有效期为365天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体