1446282-38-7

Description: Ald-CH2-PEG5-azide is a crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. The aldehyde group reacts with amines and the N-terminal of peptides and proteins to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage.

Name: Ald-CH2-PEG5-azide
CAS#: 1446282-38-7
Chemical Formula: C12H23N3O6
Exact Mass: 305.1587
Molecular Weight: 305.33
Elemental Analysis: C, 47.21; H, 7.59; N, 13.76; O, 31.44

Synonym: Ald-CH2-PEG5-azide

IUPAC/Chemical Name: 17-azido-3,6,9,12,15-pentaoxaheptadecanal

InChi Key: VYTIEPBAXZXQJS-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H23N3O6/c13-15-14-1-3-17-5-7-19-9-11-21-12-10-20-8-6-18-4-2-16/h2H,1,3-12H2

SMILES Code: [H]C(COCCOCCOCCOCCOCCN=[N+]=[N-])=O

Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00