枸橼酸马罗匹坦|Maropitant Citrate|359875-09-5 新品

产品描述

等级：活性药物成分（API）

化学名称：(2S,3S)-2-苄基- n-[（5-叔丁基-2-甲氧基苯基）甲基]-1-氮杂二环[2.2.2]辛烷-3-胺-2-羟基丙烷-1,2,3-三羧酸水合物

分子式：C17H21FN4

分子量：300.37400

规范：按照ChP/USP/EP建立企业标准

外观:粉

总杂质：不大于2.0%

纯度：不低于98%

残留溶剂：完全符合ICH Q3C要求

致突变杂质：完全符合ICH M8

亚硝胺评估：可用

粒度：可根据客户要求进行普通级或研磨/筛分。

储存方法：室温

标准包装：1kg/袋，5kg/袋，或根据客户要求

产品用途

Maropitant专门用于治疗狗的晕动病和呕吐。2007年，FDA批准将其用于狗，2012年批准将其用于猫。

马洛匹坦有轻微的止痛、抗焦虑和抗炎作用。

枸橼酸马洛匹坦注射液用于预防和治疗犬急性呕吐；马洛匹坦柠檬酸片用于预防狗的急性呕吐和预防因运动病引起的呕吐。这两种药物在猫的标签外也有使用。

联系方式

四川青木制药有限公司

四川省眉山市东坡区经济开发区东区顺江大道南段55号

国际营销部(International):

Email: sales@eastonpharma.cn 

Tel: 028-87827187

国内营销部(Mainland)：

李经理 13880480517   

杨经理 15982276454

Product Description

• Grade: Active Pharmaceutical Ingredient(API)

• ChemicalName: (2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine,2-hydroxypropane-1,2,3-tricarboxylic acid,hydrate

• Molecular Formula: C17H21FN4

• Molecular Weight: 300.37400

• Specification: Enterprise Standard established according to ChP/USP/EP

• Appearance: Powder

• Total impurities: not more than 2.0%

• Purity: not less than 98%

• Residual Solvents: fully comply with ICH Q3C

• Mutagenic impurities: fully comply with ICH M8

• Nitrosamine assessment: available

• Particle size: regular grade or milling/sieving according to customer’s requirement.

• Storage: Room temperature

• Production capacity: Maropitant Citrate

• Standard Package: 1kg/bag, 5kg/bag, or according to the customer’s requirement

Applications 

• Maropitant (INN; brand name: Cerenia, used as maropitant citrate (USAN), is a neurokinin-1 (NK1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs and in 2012, for cats.

• Maropitant has mild pain-relieving, anti-anxiety, and anti-inflammatory effects.

• Maropitant citrate injectable solution is indicated for the prevention and treatment of acute vomiting in dogs; maropitant citrate tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs. Both are also used extra-label in cats.

Contact Information

Sichuan Qingmu Pharmaceutical Co., Ltd.

Add: No. 55, South Shunjiang Avenue, East Economic Development Zone, Dongpo District, Meishan City, Sichuan, 620036, China

International Marketing Department: 

Email: sales@eastonpharma.cn 

Tel: 0086-28-87827187